Baby food - milk

AGROLAB LUFA GmbH has established a method for the determination of nucleotides by HPLC, which are important for the development of newborns.


Nucleotides are biological compounds that play a key role in almost all biological processes in the human body. They are constantly synthesised, degraded and restored in the body. In phases of strong growth, there is an increased need for nucleotides, such as newborns. So it is not surprising that nucleotides are naturally present in human milk. Among other things, nucleotides stimulate the immune system and promote the formation of antibodies.

According to Regulation (EU) No. 609/2013, the following nucleotides may also be added to infant formulae and follow-on formulae:

  • Adenosine-5'-monophosphate (AMP)
  • Cytidine-5'-monophosphate (CMP)
  • Guanosine 5'-monophosphate (GMP)
  • Inosine 5'-monophosphate (IMP)
  • Uridine 5'-monophosphate (UMP)

However, maximum levels of the individual nucleotides and the sum of all nucleotides must be complied in infant formulae as well as in follow-on formulae (Commission Delegated Regulation (EU) 2016/127).


AGROLAB LUFA GmbH has established a method for the determination of these five 5'-monophosphate nucleotides by HPLC (ISO 20638:2015-11 (mod.)) for milk-based infant formulae which allows you to reliably check compliance with the maximum levels.


With this, the AGROLAB LUFA GmbH is further expanding their already comprehensive range of analytics for infant nutrition.



Author: Dr. Katja Fuchs